hrp0095p1-428 | Bone, Growth Plate and Mineral Metabolism | ESPE2022

Extra-articular calcification in an adolescent boy: where history is paramount

Rodrigues Farrah , Zacharin Margaret

A 15-year-old boy, an active sportsperson, presented to an orthopaedic surgeon with a painful left elbow. He had no history of preceding trauma, had full range of motion of his elbow and was systemically well. Imaging demonstrated extra articular calcification at the distal humerus. Serum phosphate was elevated at 2.53mmol/l [1.10-1.80] with calcium 2.48mmol/l [2.10-2.60] and tubular reabsorption of phosphate of 94.6% [82-100%]. He was then referred for endocrine assessment, w...

hrp0095p1-376 | Sex Differentiation, Gonads and Gynaecology, and Sex Endocrinology | ESPE2022

A virilizing ovarian tumour following previous rhabdomyosarcoma, masking ovarian failure

Rodrigues Farrah , Zacharin Margaret

An 11 year 8-month-old girl presented to her oncologist with recent voice change and increased leg hair growth. She had a past history of pelvic rhabdomyosarcoma in 2012, at age 2, with relapse and local metastasis at age 4. Prior to original tumour treatment, oophoropexy had been performed, aiming to prevent ovarian radiation exposure. At time of the new complaint, she was receiving a trial treatment. Puberty was reported to have commenced at age 10, with 6-months of increase...